A samurai lord has bartered away his newborn son's organs to forty-eight demons in exchange for dominance on the battlefield. Yet, the abandoned infant survives thanks to a medicine man who equips him with primitive prosthetics—lethal ones with which the wronged son will use to hunt down the multitude of demons to reclaim his body one piece at a time, before confronting his father. On his journeys the young hero encounters an orphan who claims to be the greatest thief in Japan.
Japan, 1860. The men of the Mito clan, victims of the Ansei purge, anxiously prowl around the Sakurada Gate of Edo Castle with the intention of assassinating Naosuke Ii of Hikone, tairō of the Tokugawa shogunate and responsible for their misfortune.
The 13 Lords of the Shogun
Following the ascension to power of Taira no Kiyomori, the Minamoto clan is exiled. Minamoto no Yoritomo meets Masako, the sister of Hōjō Yoshitoki and later marries her. Following this marriage, the gears of Yoshitoki's destiny begin to turn.